For multi-select boxes where you have a list of things you want to filter on, and you want the queryset returned to be an OR'd set.
qset = Q(mode__exact=modes[0])
if len(modes) > 1:
for mode in modes[1:]:
qset = qset | Q(mode__exact=mode)
r = Responses.objects.filter(qset)
Now, I need to figure out how to do this as a list comprehension!
For extra coolness, you can see what SQL you're generating:
print r.query.as_sql()